Prebiotic chemical kinetics imprint on positional codon usage

Journal of the Brazilian Chemical Society

Ferreira, Ricardo¹  Universidade Federal de Pernambuco, Recife, Brazil¹  Pacific Northwest National Laboratory, Richland, USA¹  Lai, Kevin¹  Lins, Roberto D.¹ 

关键词: codon usage;    pre-biotic Earth;    molecular evolution;    data mining;    RefSeq;   

DOI  :  10.1590/S0103-50532010000600022

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Over one million exons across the three Domains of Life have been analyzed and a significant excess of first codons containing identical bases in their first two positions has been found in Eubacteria and Archaea genomes. This frequency is observed to be much lower in the genome of Eukarya. This discrepancy is proposed to depend on the kinetics of oligoribotide/oligoribotide-like growth in the primeval Earth, toned down during further evolution.

【 授权许可】

Unknown