Synthesis and structural characterization of block and random low molecular weight copolymers composed of L-lactic acid and isosorbide succinate moieties

Journal of the Brazilian Chemical Society

Petri, Denise F. S.¹  New Jersey Institute of Technology, Newark, USA¹  Casarano, Romeu¹  Universidade de São Paulo, São Paulo, Brazil¹  Catalani, Luiz H.¹  Jaffe, Michael¹ 

关键词: isosorbide;    PLLA;    PIS;    copolymers;    MALDI-TOF;   

DOI  :  10.1590/S0103-50532009000800005

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Isosorbide succinate moieties were incorporated into poly(L-lactide) (PLLA) backbone in order to obtain a new class of biodegradable polymer with enhanced properties. This paper describes the synthesis and characterization of four types of low molecular weight copolymers. Copolymer I was obtained from monomer mixtures of L-lactide, isosorbide, and succinic anhydride; II from oligo(L-lactide) (PLLA), isosorbide, and succinic anhydride; III from oligo(isosorbide succinate) (PIS) and L-lactide; and IV from transesterification reactions between PLLA and PIS. MALDI-TOFMS and 13C-NMR analyses gave evidence that co-oligomerization was successfully attained in all cases. The data suggested that the product I is a random co-oligomer and the products II-IV are block co-oligomers.

【 授权许可】

Unknown