期刊论文详细信息
Journal of the Brazilian Chemical Society
Microwave-assisted reaction of 2,3-dichloronaphthoquinone with aminopyridines
Pontificia Universidad Católica de Chile, Santiago, Chile1  Tapia, Ricardo A.1  Cuéllar, Mauricio1  Universidad de Valparaíso, Valparaíso, Chile1  Cantuarias, Lorena1  Villena, Joan1 
关键词: 2;    3-dichloronaphthoquinone;    microwave irradiation;    aminopyridines;    cytotoxic activity;   
DOI  :  10.1590/S0103-50532009000500027
学科分类:化学(综合)
来源: SciELO
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【 摘 要 】

The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro-1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line.

【 授权许可】

Unknown   

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