An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium: product identification by gas chromatography-mass spectrometry (GC-MS)

Journal of the Brazilian Chemical Society

Universidade Federal de Minas Gerais, Belo Horizonte, Brazil¹  Augusti, Rodinei¹  Alves, Tânia M. A.¹  Fundação Oswaldo Cruz, Belo Horizonte, Brazil¹  Dalmázio, Ilza¹ 

关键词: paracetamol;    advanced oxidation process;    GC-MS;   

DOI  :  10.1590/S0103-50532008000100013

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The advanced oxidation of paracetamol (1) promoted by TiO2/UV system in aqueous medium was investigated. Continuous monitoring by several techniques, such as UV-Vis spectroscopy, HPLC (high performance liquid chromatography), TOC (total organic carbon), and ESI-MS (electrospray ionization mass spectrometry), revealed that whereas the removal of paracetamol was highly efficient under these conditions, its mineralization was not likewise accomplished. GC-MS (gas chromatography-mass spectrometry) analysis showed that hydroquinone, aliphatic carboxylic acids, monohydroxy and dihydroxy paracetamol were the main products formed as a result of such degradation process. Based on these results, a reaction route for the degradation of paracetamol induced by the TiO2/UV system was suggested. Fragmentation pathways, as obtained from the mass spectra data, were also proposed for the trimethylsilyl (TMS) derivatives of monohydroxy and dihydroxy paracetamol.

【 授权许可】

Unknown