3-Ishwarone and 3-Ishwarol, rare sesquiterpenes in essential oil from leaves of Peperomia oreophila Hensch.

Journal of the Brazilian Chemical Society

Jardim Botânico do Rio de Janeiro, Rio de Janeiro, Brazil¹  Oliveira, Alberto de¹  Guimarães, Elsie F.¹  Kato, Massuo J.¹  Lago, João Henrique G.¹  Universidade Presbiteriana Mackenzie, São Paulo, Brazil¹  Universidade de São Paulo, São Paulo, Brazil¹ 

关键词: Peperomia oreophila;    essential oil;    ishwarane sesquiterpenes;    3-ishwarol;    3-ishwarone;   

DOI  :  10.1590/S0103-50532007000300022

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The essential oil from Peperomia oreophila leaves (Piperaceae) was submitted to fractionation in silica gel column. This separation procedure yielded a fraction composed of a hydrocarbon sesquiterpene mixture which was identified as b-elemene, a-ylangene, a-guaiene and b-selinene. Besides, spathulenol and two sesquiterpenes with the rare ishwarane skeleton: 3-ishwarol and 3-ishwarone were also identified. 3-ishwarone was the major component of the crude oil (78% weight). Since the alcohol obtained was not sufficient to allow a complete structural determination, the original ketone was reduced to 3-ishwarol in order to give additional quantities. After the two sesquiterpenes purification, they were characterized by spectrometric techniques (1H-1H COSY, HMQC, HMBC and NOESY).

【 授权许可】

Unknown