Pyrrolizidine alkaloids from Heliotropium indicum

Journal of the Brazilian Chemical Society

Braz-Filho, Raimundo¹  Machado, Luciana L.¹  University of Illinois at Chicago, USA¹  Yao, Ping¹  Lemos, Telma L. G.¹  Pessoa, Otília D. L.¹  Cordell, Geoffrey A.¹  Universidade Federal do Ceará, Fortaleza, Brazil¹  Souza, João Sammy N.¹  Overk, Cassia R.¹  Universidade Estadual do Norte Fluminense, Campos, Brazil¹ 

关键词: Heliotropium indicum;    Boraginaceae;    pyrrolizidine alkaloids;    antioxidant activity;   

DOI  :  10.1590/S0103-50532005000800019

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Helindicine (1), a new pyrrolizidine alkaloid with unusual structural features, together with the known lycopsamine (2), were isolated from the roots of Heliotropium indicum (Boraginaceae). The structures were established by a combination of 1D and 2D NMR methods (COSY, HMQC, HMBC, and NOESY) and HREIMS. This is the first report of a lactone pyrrolizidine alkaloid in the genus Heliotropium. Compounds 1 and 2 were assayed for antioxidant activity and showed moderate activity.

【 授权许可】

Unknown