期刊论文详细信息
| Journal of the Brazilian Chemical Society | |
| An easy and efficient method to produce gamma-amino alcohols by reduction of beta-enamino ketones | |
| Universidade Estadual de Campinas, Campinas, Brazil1 Harris, Maria Inês N. C.1 Braga, Antonio C. H.1 | |
| 关键词: amino alcohols; enamino ketones; oxazines; stereoselective reduction; | |
| DOI : 10.1590/S0103-50532004000600027 | |
| 学科分类：化学（综合） | |
| 来源: SciELO | |
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【 摘 要 】
Reduction of b-enamino ketones 2 with NaBH4 in glacial acetic acid gave g-amino alcohols 1 in 70% to 98% yield with diastereomeric excesses, preferentially the syn product, from 44% to 90%. The stereochemistry of these compounds was confirmed by analysis of their tetrahydro-1,3-oxazine derivatives 3.
【 授权许可】
Unknown
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201912050579632ZK.pdf | 150KB |  download |
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