Voltammetric determination of dipyrone using a N,N'-ethylenebis(salicylideneaminato)oxovanadium(IV) modified carbon-paste electrode

Journal of the Brazilian Chemical Society

Marcolino-Júnior, Luiz H.¹  Universidade Federal de São Carlos, São Carlos, Brazil¹  Cavalheiro, Éder T. G.¹  Teixeira, Marcos F. S.¹  Dockal, Edward R.¹  Universidade de São Paulo, São Carlos, Brazil¹  Universidade Estadual Paulista, São Vicente, Brazil¹  Fatibello-Filho, Orlando¹ 

关键词: N;    N'-ethylenebis(salicylideneiminato)oxovanadium(IV);    modified electrode;    voltammetric determination;    dipyrone;    pharmaceutical formulations;   

DOI  :  10.1590/S0103-50532004000600003

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The preparation and electrochemical characterization of a carbon paste electrode modified with N,N'-ethylenebis(salicylideneiminato)oxovanadium(IV) complex ([VO(Salen)]) as well as its behavior as electrocatalyst toward the oxidation of dipyrone were investigated. The electrochemical behavior of the modified electrode and the electrooxidation of dipyrone were explored using cyclic voltammetry. The voltammetric response of the modified electrode is based on two reactions. One electrochemical related to the oxidation of the metallic center of the [VO(Salen)] and the other involving the chemical redox process involving the oxidized form of the complex and the reduced form of dipyrone. The best voltammetric response was observed for a paste composition of 25% (m/m) [VO(Salen)], KCl solution pH from 5.5 to 8.0 as the electrolyte and potential scan rate of 10 mV s-1 in the presence of dipyrone. A linear voltammetric response for dipyrone was obtained in the concentration range from 9.9 x 10-6 to 2.8 x 10-3 mol L-1, with a detection limit of 7.2 x 10-6 mol L-1. Among of several compounds tested as potential interference, only ascorbic acid presented some interference. The proposed electrode is useful for the quality control and routine analysis of dipyrone in pharmaceutical formulations.

【 授权许可】

Unknown