Chemical transformation of abietic acid to new chiral derivatives

Journal of the Brazilian Chemical Society

Santos, Catarina dos¹  Universidade Estadual de Campinas, Campinas, Brazil¹  Universidade Federal de São Carlos, São Carlos, Brazil¹  Imamura, Paulo M.¹  Zukerman-Schpector, Julio¹ 

关键词: abietic acid;    ozonization;    chiral synthon;    abeo-abietane derivatives;   

DOI  :  10.1590/S0103-50532003000600017

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Chemical transformations of the C-ring abietic acid (1a) for the preparation of some new chiral synthons are described. From the intermediate keto-aldehyde 9, readily available from 1b through the ozonide 2, the new tetracyclic diterpene 4 was synthesized. Additionally, from 13 and 17, previously prepared from 2, the bicyclic compounds 14, 15 and 16 and the derivatives containing the abeo-abietane[6,6,5] framework 19 and 20 were also synthesized.

【 授权许可】

Unknown