The use of solid phase reactors as the source of a catalytic solution: the indirect flow-injection spectrophotometric determination of amino acids

Journal of the Brazilian Chemical Society

Gil Torró, J.V¹  Garcia Mateo,¹  Martínez Calatayud, J.¹ 

关键词: Cu(II) catalyst;    spectrophotometry;    glycine;    amino acids;    flow analysis;    solid-phase reactors;   

DOI  :  10.1590/S0103-50531997000100011

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The indirect determination of amino acids is carried out in a flow-injection assembly by means of a solid-phase reactor containing cupric salts, immobilized in polyester resin beads. A pharmaceutical substance is forced through the reactor and the released cupric ions (complexed by the pharmaceutical substance) act as a catalyst for the subsequent reaction between Fe(III) and sodium thiosulfate. The calibration graph is linear over the range 0.1-3.0 µg mL-1 glycine, the RSD was 2.3%, and the sample throughput was 28 h-1. The influence of foreign substances was studied and the method was applied to the determination of glycine in two different pharmaceutical formulations.

【 授权许可】

Unknown