The risk of herpes zoster in the anti-TNF-α era: a case report and review of the literature

Journal of Dermatological Case Reports

Fabio Ayala¹  Matteo Megna¹  Francesca Gaudiello¹  Angela Patrì¹  Luisa Di Costanzo¹  Nicola Balato¹ 

[1] Department of Dermatology – University of Naples Federico II, Naples, Italy.

关键词: adalimumab;    biological therapy;    etanercept;    herpes zoster;    infliximab;    psoriasis;    viral infection;   

DOI  :  10.3315/jdcr.2013.1126

学科分类：皮肤病学

来源: Specjalisci Dermatolodz

【 摘 要 】

Tumor necrosis factor-α (TNF-α) inhibitors represent efficacious therapeutic agents in many chronic inflammatory diseases such as psoriasis and rheumatoid arthritis. However they have been connected with increased risk of infection and reactivation of a variety of infectious agents, such as viruses. The reactivation of varicella zoster virus infection causes herpes zoster (HZ), a self-limiting, dermatomally localized, vesicular rash that can be accompanied by postherpetic neuralgia and severe neurological complications.

【 授权许可】

Unknown