Pseudoephedrine for the Treatment of Clozapine-Induced Incontinence

Innovations in Clinical Neuroscience

Tammie Lee Demler¹  Alicia Hanes¹  Alexander Campos¹  Claudia Lee¹ 

[1] Drs. Hanes and Compos are from University at Buffalo, School of Pharmacy and Pharmaceutical Sciences, Buffalo, New York; Drs. Demler and Lee are from Buffalo Psychiatric Center, Buffalo, New York.

关键词: Clozapine;    drug-induced;    pseudoephedrine;    ephedrine;    urinary incontinence;    Major depressive disorder;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Clozapine, the first atypical antipsychotic, is well known for superior efficacy in the treatment of refractory schizophrenia. Though the side effect most often associated with clozapine is the potential for causing blood dyscrasias, other lesser known side effects, including clozapine-induced incontinence, may result in the unnecessary discontinuation of this essential psychiatric medication in patients who otherwise have no alternative to treatment. Here we describe a case of pseudoephedrine used successfully as a therapeutic intervention for clozapine-induced incontinence.

【 授权许可】

Unknown