Comparison of the Peak-to-trough Fluctuation in Plasma Concentration of Long-acting Injectable Antipsychotics and Their Oral Equivalents

Innovations in Clinical Neuroscience

Dong-Jing Fu¹  Kristin R. Reilly¹  Larry Alphs¹  John J. Sheehan¹ 

[1] Dr. Sheehan was an employee of Janssen Scientific Affairs, LLC, Titusville, New Jersey, at the time of this analysis and is currently an employee of Bristol-Myers Squibb, Plainsboro, New Jersey; Drs. Reilly, Fu, and Alphs are employees of Janssen Scientific Affairs, LLC, Titusville, New Jersey.

关键词: Peak-to-trough fluctuation;    antipsychotic;    long-acting injectable;    oral;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Background: Small peak-to-trough drug levels have been suggested to be related to improved tolerability. The aim of this study is to review the steady-state, peak-to-trough, plasma-concentration fluctuation of long-acting injectable antipsychotics and equivalent oral formulations.

【 授权许可】

Unknown