Are Antidepressants Effective in the Acute and Long-term Treatment of Depression? Sic et Non

Innovations in Clinical Neuroscience

Ronald Pies¹ 

[1] Dr. Pies is Professor of Psychiatry, SUNY Upstate Medical University, Syracuse, New York, and Clinical Professor of Psychiatry, Tufts University School of Medicine, Boston, Massachussetts

关键词: Antidepressants;    acute treatment;    maintenance treatment;    placebo effect;    relapse;    recurrence;    oppositional tolerance;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

The efficacy of antidepressant treatment of major depression remains a matter of controversy. A review of acute treatment studies suggests that for relatively more severe episodes of major depression, antidepressants are superior to treatment in the “placebo group;” however, there are numerous methodological confounds in the available literature. (Some recent, preliminary evidence suggests that antidepressants may also be of benefit in some less severely depressed populations).

【 授权许可】

Unknown