Management of Erectile Dysfunction in the Hypogonadal Man: A Case-Based Review

Reviews in Urology

Nathan A Wilken¹  Larry I Lipshultz¹  Jason R Kovac¹  Jason M Scovell¹  Ranjith Ramasamy¹ 

[1] Scott Department of Urology, Baylor College of Medicine,, Houston, TX

关键词: Erectile dysfunction;    Testosterone supplementation;    Hypogonadism;    Phosphodiesterase type 5 inhibitors;   

DOI  :  

学科分类：基础医学

来源: MedReviews, LLC

【 摘 要 】

Erectile dysfunction (ED) has emerged as an important marker of cardiovascular and overall health, independent of other known conventional risk factors. ED often precedes coronary artery disease in half of affected subjects, and could indicate the presence of cardiovascular pathology. The pathophysiology and role of androgens in sexual function are described, along with the relevant literature on the effects of aging in erectile and gonadal function. The concept of testosterone supplementation (TST) in men with ED is reviewed. The authors utilize clinical vignettes to discuss the appropriate management of two clinical cases of men at different life stages who have ED in the setting of hypogonadism and propose a treatment algorithm. In patients of all ages, proper identification of the underlying pathophysiology of decreased libido and erectile function is paramount in choosing between the use of TST, phosphodiesterase type 5 inhibitors, or both, in the management of these disorders.

【 授权许可】

Unknown