Surgical Options for Drug-Refractory Overactive Bladder Patients

Reviews in Urology

Christopher P Smith³  Jonathan S Starkman²  David R Staskin¹ 

[1] Caritas-St. Elizabeth’s Medical Center Associate Professor of Urology, Tufts University School of Medicine, Boston, MA;Pioneer Valley Urology PC, Female Pelvic Medicine and Reconstructive Surgery, Springfield, MA;Scott Department of Urology, Baylor College of Medicine, Houston, TX

关键词: Overactive bladder syndrome;    Urinary urgency incontinence;    Muscarinic receptor-blocking agents;    Posterior tibial nerve stimulation;    Sacral neuromodulation;    Botulinum neurotoxins;   

DOI  :  

学科分类：基础医学

来源: MedReviews, LLC

【 摘 要 】

Overactive bladder (OAB) is a symptom complex of urinary frequency, urinary urgency, and nocturia, with or without urgency incontinence. This syndrome is idiopathic in most instances without clearly defined pathophysiology. Studies clearly show that OAB negatively impacts health-related quality of life and impairs daily functioning in a large proportion of patients. Despite recent advances in drug delivery and improved tolerability of antimuscarinic drug class, a large percentage of patients remain refractory to conventional pharmacological therapy for this chronic condition. There are several unique and effective treatments that are available for this difficult population. We review the various surgical options within the urological armamentarium to treat patients with refractory OAB.

【 授权许可】

Unknown