Concomitant Medications and Possible Side Effects of Antimuscarinic Agents

Reviews in Urology

Scott A MacDiarmid¹ 

[1] Alliance Urology Specialists, Bladder Control and Pelvic Pain Center, Greensboro, NC

关键词: Overactive bladder;    Antimuscarinic agents;    Side effects;    Tolterodine;    Solifenacin;    Oxybutynin;    Darifenacin;    Trospium chloride;    Elderly;   

DOI  :  

学科分类：基础医学

来源: MedReviews, LLC

【 摘 要 】

Antimuscarinic agents are the treatment of choice for overactive bladder syndrome; clinical experience and the literature support their efficacy, tolerability, and safety. The most common side effects experienced include dry mouth and constipation. Many commonly prescribed drugs have anticholinergic effects that could increase the anticholinergic “load” or “burden” in patients with overactive bladder, potentially increasing the frequency and severity of side effects. In addition, the adverse events associated with antimuscarinics may be more pronounced in the elderly, especially those taking multiple medications. Knowledge regarding the potential side effects associated with antimuscarinics is important so that patients can be advised and effectively treated.

【 授权许可】

Unknown