Challenges for Production of Human Transplantable Organ Grafts

Cell Medicine

Kobayashi, Eiji¹ 

DOI  :  10.3727/215517916X693113

学科分类：生物科学（综合）

来源: Cognizant Communication Corporation

【 摘 要 】

The described research methods explain how you could generate a three-dimensional kidney, based on recent research results. The first method is to fabricate human organs in a pig body. The second is to transplant the so-called “organ bud” into a patient’s body forfurther development. The third method is to regenerate organs by filling cells into the cytoskeleton as a scaffold. Research for the in vitro fabrication of organ buds has been elaborately accelerated. The organ bud transplantation has been confronted with issues of continuity with the originalorgans, so the development of technology for achieving continuity between a transplanted organ bud and the existing organs is progressing well. The “organ fabrication” methodology, whereby cells are placed into completely decellularized organs, is supported by recent research resultsusing pig organs taking the size of humans into consideration.

【 授权许可】

Unknown