Effect of Combined Therapy Using Diode Laser and Photodynamic Therapy on Levels of IL-17 in Gingival Crevicular Fluid in Patients With Chronic Periodontitis

Journal of Lasers in Medical Sciences

Vineet Kini¹  Richard Pereira¹  Ashvini Padhye¹  Abhishek Mistry¹ 

[1] Department of Periodontics, Mahatma Gandhi Mission’s Dental College and Hospital, Junction of NH4 and Sion-Panvel Expressway, Kamothe, Navi Mumbai- 410209, India$$

关键词: Keywords: Periodontitis;   

DOI  :  10.22037/2010.v7i4.10826

学科分类：基础医学

来源: Shahid Beheshti University of Medical Sciences

【 摘 要 】

Introduction: The aim of this study was to evaluate the efficacy of combination therapy of diode laser and photodynamic therapy (PDT) as an adjunct to scaling and root planing (SRP) on interleukin-17 (IL-17) levels in gingival crevicular fluid (GCF) in patients with chronic periodontitis. Methods: Thirty subjects with chronic periodontitis were included. All teeth received periodontal treatment comprising of SRP. Using a split mouth study design, the test group was additionally treated with a combination therapy of diode laser and PDT. GCF was collected to evaluate IL-17 levels at baseline and 3 months. Results: There was no difference in baseline values for levels of IL-17 in GCF in the test group and the control group. A significant decrease in GCF levels of IL-17 was observed in both treatment groups 3 months after treatment ( P < 0.001). However, the treatment groups showed no significant difference ( P > 0.05). Conclusion: Based on the results of the present study it was concluded that, GCF levels of IL-17 changed significantly after treatment regardless of treatment modality.  

【 授权许可】

Unknown