In Women Myocardial Infarction Occurrence is Much Stronger Related to Environmental Physical Activity than in Men - a Gender or an Advanced Age Effect?

Journal of Clinical and Basic Cardiology

Sulkes J¹  Domarkiene S¹  Israelevich P¹  Abramson E¹  Stoupel E¹  Radishauskas R¹ 

[1] $$

关键词: Alter;    Frau;    Geschlecht;    Kardiologie;    Myokardinfarkt;    physische Aktivität;    AGE;    cardiology;    gender;    myocardial infarction;    Physical Activity;    woman;   

DOI  :  

学科分类：心脏病和心血管学

来源: Krause & Pachernegg GmbH

【 摘 要 】

Background: Despite continuous effect of the recognised risk factors time distribution of acute coronary events differs. Environmental influences are a long time investigated as possible triggers of time related fluctuations. The aim of this study was to check possible links between the monthlynumbers of acute myocardial infarction (AMI) (in the pre-troponin era) in general, and in woman and man, with 3 groups of cosmophysicalactivity indices: solar, geomagnetic (GMA), and cosmic rays (close related to space proton flux at high energy > 90–100 MEV) levels.Material and Methods: The monthly numbers of AMI in the years 1983–1999 (204 consecutive months) from the Kaunas registry wereanalysed (16,683 patients total; 10,405 male, 6,478 female). Cosmophysical indices were: solar – sunspot numbers and solar flux at 2,800 MGH,10.7 cm wavelength, for GMA monthly Ap., Cp., and Am. Indices; for cosmic rays – neutron monitoring data of solar and GMA was obtainedfrom the National Geophysical and Space Service Centers, USA. For cosmic rays activity – from Apatity Neutron Monitor Station of theRussian Academy of Sciences.Statistics: Pearson correlation coefficients (r) and their probabilities (p) were calculated, describing 95 % and higher probabilities as significant and85–94 % as trends.Results: For the whole group it was a significant inverse correlation with solar and GMA indices and a correlation with cosmic rays activity level.For women, despite the smaller absolute number of AMI, compared with men, the correlation indices were 2–3 times higher, and also theprobabilities. The differences can be explained a) by gender differences in reaction to changes in levels of environmental physical activity and/or b)the higher age in general, that women suffer AMI compared to men.Conclusion: The monthly number of acute myocardial infarction correlates with solar, geomagnetic, and cosmic rays activity. This relationship is 2–3 times stronger for women. Gender and/or higher age of suffering myocardial infarction of women can be related to the observed gender differences.

【 授权许可】

Unknown