Treatment and follow-up using microscopy and polymerase chain reaction in East African sleeping sickness: a case report

Grand Rounds

E.A. Hamminga¹  L.M.A. Vingerhoets¹  J.J. Verweij¹  M.P. Bauer¹  L.G. Visser¹ 

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关键词: Trypanosoma brucei rhodesiense;    sleeping sickness;    suramin;   

DOI  :  10.1102/1470-5206.2011.0003

学科分类：传染病学

来源: e-MED Ltd.

【 摘 要 】

We report a case of East African trypanosomiasis in a 26-year-old traveler returning from Tanzania, including a series of pictures of the progression of the inoculation chancre. Trypanosoma brucei rhodesiense-specific DNA was detected in the blood until 8 days after treatment. We hypothesize that the previously observed suramin toxicity may be an immunological response to parasite debris, produced as they are killed by the treatment.

【 授权许可】

Unknown