期刊论文详细信息
Journal of Chemical Sciences
One pot synthesis of 1-substituted tetrahydro-𝛽-carbolines by Bischler–Napieralski cyclization
Okram Mukherjee Singh11  Thokchom Prasanta Singh1 
[1] Chemistry Department, Manipur University, Canchipur 795 003, Manipur, India$$
关键词: Bischler–Napieralski reaction;    tetrahydro-𝛽-carboline;    ketene 𝑆;    𝑆–acetals;    InCl3;    one-pot.;   
DOI  :  
来源: Indian Academy of Sciences
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【 摘 要 】

A novel and facile one-pot synthesis of 1-substituted tetrahydro-𝛽-carbolines by cyclocondensation of ketene 𝑆,𝑆–acetals with tryptamine in presence of InCl3 and TFA as co-catalysts by Bischler-Napieralski cyclization is described. The reaction involves formation of one C-N bond, one C-C bond and a new ring annulation over an indole moiety.

【 授权许可】

Unknown   

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