期刊论文详细信息
Journal of Chemical Sciences | |
One pot synthesis of 1-substituted tetrahydro-ð›½-carbolines by Bischler–Napieralski cyclization | |
Okram Mukherjee Singh11 Thokchom Prasanta Singh1 | |
[1] Chemistry Department, Manipur University, Canchipur 795 003, Manipur, India$$ | |
关键词: Bischler–Napieralski reaction; tetrahydro-ð›½-carboline; ketene ð‘†; ð‘†â€“acetals; InCl3; one-pot.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
A novel and facile one-pot synthesis of 1-substituted tetrahydro-ð›½-carbolines by cyclocondensation of ketene ð‘†,ð‘†â€“acetals with tryptamine in presence of InCl3 and TFA as co-catalysts by Bischler-Napieralski cyclization is described. The reaction involves formation of one C-N bond, one C-C bond and a new ring annulation over an indole moiety.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201912040509244ZK.pdf | 105KB | download |