An efficient and convenient synthesis of N-substituted amides under heterogeneous condition using Al(HSO4)3 via Ritter reaction

Journal of Chemical Sciences

Elnaz Karimian¹  Batool Akhlaghinia1²  Sara S E Ghodsinia¹ 

[1] $$;Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran$$

关键词: Aluminum hydrogen sulfate [Al(HSO4)3];    Ritter reaction;    N-substituted amides;    heterogeneous catalyst;    nitriles;    alcohols;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

An efficient and inexpensive synthesis of N-substituted amides from the reaction of aliphatic and aromatic nitriles with various benzylic alcohols (secondary and tertiary) and tert-butyl alcohol by refluxing nitromethane via the Ritter reaction catalyzed by aluminum hydrogen sulfate [Al(HSO4)3] is described. Thecatalyst which is an air-stable, cost-effective solid acid could be readily recycled by filtration and reused four times without any significant loss of its activity.

【 授权许可】

Unknown