Transition metal-free, base-promoted hydroalkoxylation:Synthesis of substituted imidazo[2,1-c][1,4]oxazines

Journal of Chemical Sciences

Shanmugam Muthusubramanian1¹  Muthupandi Nagaraj² 

[1] Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India$$;$$

关键词: 1;    4-Oxazines;    hydroalkoxylation;    6-exo-dig;    regioselectivity;    1;    5-alkynyl alcohol.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

An efficient,transition metal-free method to synthesize substituted imidazo[2,1-c][1,4]oxazine derivatives via hydroalkoxylation of 1,5-alkynyl alcohol has been described. The reaction proceeds regioselectively with exclusive formation of 6-exo-dig product.

【 授权许可】

Unknown