Choline-based biodegradable ionic liquid catalyst for Mannich-type reaction

Journal of Chemical Sciences

XING RONG1²  PENG HUAN²  FANG DONG1 2²  HU YULIN¹ 

[1] School of Chemistry & Environmental Engineering, Yancheng Teachers University, Yancheng 224002, People’s Republic of China$$;College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, People’s Republic of China$$

关键词: Mannich-type reaction;    choline;    Lewis-Brønsted acid;    catalysis;    biodegradation.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

A three-component Mannich-type reaction of aromatic aldehydes, ketones, and amines was catalyzed by a novel choline-based acidic ionic liquid. The proposed catalyst was a Lewis-BrØnsted dual acid catalyst as well as water-tolerant. The β-amino carbonyl compounds were obtained at room temperature in reasonable to good yields ranging from 63 to 98%. After the reaction, the catalyst could be recycled and reused for 5 times without obvious decrease of the yield. Further, the catalyst was environment-friendly with a significant biodegradation rate.

【 授权许可】

Unknown