Synthesis, Spectroscopic Properties and DFT Calculation of Novel Pyrrolo[1',5'-a]-1,8-naphthyridine Derivatives through a Facile One-pot Process

Journal of Chemical Sciences

BO ZHOU²  WEI LIU²  CHAO-YONG MANG3³  HE-PING YAN²  SHAO-MING CHI¹  GAO-ZHANG GOU²  YONG HONG² 

[1]College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650092, P. R. China$$

[2]School of Science, Honghe University, Mengzi, Yunnan 661199, P. R. China$$

[3]College of Pharmaceutical Science and Chemistry, Dali University, Dali, Yunnan 671000, P. R. China$$

关键词: Indolizine;    1;    8-naphthyridine;    density functional theory;    crystal structure;    spectroscopic properties.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Novel pyrrolo[1',5'-a]-1,8-naphthyridine compounds (L1-L4) have been synthesized through a facile one-pot process by the reaction of the corresponding 1,8-naphthyridines with aliphatic anhydride. The structures were established by spectroscopic data. Further, X-ray crystal analysis of 7-diacetamino-2,4-dimethy-1,8-naphthyridine (L1) identifies its molecular structure and reveals π-π stacking. The synthetic mechanisms for L2, L3 were studied by density functional theory calculations. And a comprehensive study of spectroscopic properties involving experimental data and theoretical studies is presented. L1 exhibited electronic absorption spectrum with λmax at ∼320 nm. L2-L4 exhibited similar electronic absorption spectra with λmax at ∼390 nm that is tentatively assigned to π→π* transition. The assignment was further supported by density functional theory (DFT) calculations.

【 授权许可】

Unknown