Synthesis and characterization of mononuclear copper(II) complexes of pyridine 2-carboxamide: Their application as catalyst in peroxidative oxidation and antimicrobial agents

Journal of Chemical Sciences

Sutapa Joardar2²  Supriya Dutta³  Suvendu Samanta1¹  Shounak Ray¹ 

[1] Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711 103, India$$;Department of Biotechnology, Neotia Institute of Technology, Management and Science, Jhinga, Diamond Harbour Road, Amira, South 24 Parganas 743 368, India$$;Department of Chemistry, Nistarini College, Deshbandhu Road, Purulia, West Bengal 723 101, India$$

关键词: Homogeneous catalysis;    Copper;    Amide ligand;    Oxidation;    Antimicrobial activity.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Four water soluble copper(II) complexes, [Cu(HL)2 (H2O)2]Cl2 (1), [Cu(HL) 2 (ClO4)2 ] (2), [Cu(HL)2 (SCN)2] (3) and [CuL 2 ]·8H 2 O (4), where HL is pyridine 2–carboxamide, have been synthesized and characterized by various spectroscopic techniques. Structures have been determined by single crystal X-ray crystallography. The pH induced inter-conversion of Cu(HL)2 (H2O)2 ]Cl2 (1) and [CuL2]·8H2O (4) through co-ordination mode switching was investigated thoroughly with the help of absorption spectroscopy. Complexes 1–3 were found to be active catalysts for the oxidation of toluene, ethyl benzene and cyclohexane in the presence of hydrogen peroxide as the oxidant under mild conditions. Toluene was oxidized to benzyl alcohol and benzaldehyde, ethyl benzene was oxidized to 1-phenylethanol and acetophenone and cyclohexane was oxidized to yield cyclohexanol and cyclohexanone Antimicrobial activities have been investigated with these copper(II) complexes against gram + ve bacteria, gram − ve bacterial and fungal species.

【 授权许可】

Unknown