Synthesis, characterization and superoxide dismutase activity of bi-copper(II)-bisacetato-𝜇−phthalicacid[bis(benzyloxy)ethyl]ester

Journal of Chemical Sciences

Pradip K Bhattacharyya¹  Babita Sarma²  Diganta Kumar Das1² 

[1] Department of Chemistry, Arya Vidyapeeth College, Guwahati, Assam, India 781 016$$;Department of Chemistry, Gauhati University, Guwahati, Assam, India 781 014$$

关键词: phthalic anhydride;    ethylene glycol;    acetate;    copper(II);    superoxide;    IC50;    DFT.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

A new binuclear copper(II) complex, bridged by the ligand phthalicacid[bis(benzyloxy)ethyl]ester, where each copper(II) is coordinated to one carboxylate (from ligand) and one acetate in square planar mode is reported. The ligand synthesized by the reaction of phthalic anhydride and ethylene glycol, has been characterized by FT-IR, 1HNMR and LCMS. The binuclear Copper(II) complex has been characterized by UV/visible spectra, FTIR spectra, EPR spectra, ESI-MS spectra, magnetic moment measurement and thermogravimetric analysis. DFT calculation has shown a Z type structure for the complex. Excellent superoxide dismutase activity with IC50 value 8.6 × 10−6 M for the complex has been observed.

【 授权许可】

Unknown