Structural, physicochemical characterization and antimicrobial activities of a new Tetraaqua bismaleato Iron(II) complex

Journal of Chemical Sciences

Nourchene Toukebri²  Amani Naouar²  Jawher Abdelhak2¹  Najla Sadfi-Zouaoui²  Badiaa Essghaier1²  Mohamed Faouzi Zid¹ 

[1] Laboratoire de Matériaux et Cristallochimie, Département de chimie, Faculté des Sciences, 2092 El Manar, Tunis, Tunisie$$;Laboratoire Microorganismes et Biomolécules Actives, Faculté des Sciences, 2092 El Manar, Tunis, Tunisie$$

关键词: Bismaleato complex;    iron(II);    single crystal;    magnetic susceptibility;    antibacterial;    antifungal activites.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Tetraaqua bismaleato iron(II) [Fe(C4H3O4)2 (H2O)4], (1) is a new synthetic antimicrobial agent. Thermal analysis shows that the dehydration of the compound occurs in agreement with the structure. The single crystal salt crystallizes in the triclinic space group 𝑃-1 with 𝑎 = 5.171(2) Å, 𝑏 = 7.309(3) Å, 𝑐 = 9.731(3) Å, 𝛼 = 109.15(2)°, 𝛽 = 115.02(2)°, 𝛾 = 92.42(1)°, 𝑉 = 313.6(3) Å3 and Z = 1. Three dimensional network is formed by strong intermolecular O – H . . . O hydrogen bonds. Magnetic susceptibility measurements of 1 in the range 2–300 K exhibited paramagnetic behavior at high temperature. However, at low temperature, the susceptibility data showed weak antiferromagnetic interactions between the local spins. Antimicrobial activity of 1 was tested. It showed high response against gram-positive and gram-negative bacteria as well as fungi and the MIC and IC50 values ranged from 8 to 256 𝜇g.mL−1 and from 1.38 to 22.19 𝜇g.mL−1, respectively.

【 授权许可】

Unknown