Green and expeditious synthesis of 1,8-dioxodecahydroacridine derivatives catalysed by protic pyridinium ionic liquid

Journal of Chemical Sciences

Heshmatollah Alinezhad¹  Mahmood Tajbakhsh¹  Saeed Baghery3²  Mohammad Norouzi1 2¹  Jamshid Rakhtshah² 

[1] Department of Chemistry, Mazandaran University, Babolsar, Iran$$;Department of Chemistry, College of Science, Bu-Ali Sina University, Hamedan, Iran$$

关键词: 2-Methylpyridinium trifluoromethanesulphonate;    Hantzsch three-component condensation;    protic ionic liquid;    1;    8-dioxodecahydroacridine;    water solvent.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

The Hantzsch three-component condensation reaction of various aromatic aldehydes, 1,3-dione and aniline derivatives in the presence of 2-methylpyridinium trifluoromethanesulphonate ([2-MPyH]OTf) as green and highly efficient catalysts in water affords 1,8-dioxodecahydroacridine derivatives in good to excellent yields. This reaction has been carried out in the presence of 1 mol% of [2-MPyH]OTf at room temperature. The described novel synthesis method proposes several advantages of mild condition, short reaction times, high yields, simplicity and easy workup compared to the traditional method of synthesis.

【 授权许可】

Unknown