Binding of reactive organophosphate by oximes via hydrogen bond

Journal of Chemical Sciences

Valentina La Paglia Fragola¹  Giuseppe Trusso Sfrazzetto1¹  Gaetano A Tomaselli¹  Andrea Pappalardo¹  Maria E Amato¹  Rosa Maria Toscano¹  Francesco P Ballistreri¹ 

[1] Dipartimento di Scienze Chimiche, Università di Catania, viale A Doria 6, 95125 Catania, Italy$$

关键词: Nerve agents;    oximes;    hydrogen bond;    organophosphate stimulant.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

In this contribution, the ability of simple oximes to bind a well-known nerve agent simulant (dimethylmethylphosphonate, DMMP) via hydrogen bond is reported. UV/Vis measurements indicate the formation of 1:1 complexes. 1H-, 31P-NMR titrations and T-ROESY experiments confirm that oximes bind the organophosphate via hydrogen bond.

【 授权许可】

Unknown