Di(1𝐻-benzo[𝑑][1,2,3]triazol-1-yl)methane: An efficient ligand for copper and amine-free palladium-catalysed Sonogashira coupling reaction

Journal of Chemical Sciences

Jaspal Singh¹  Akhilesh Kumar Verma1¹ 

[1] Synthetic Organic Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India$$

关键词: Palladium;    terminal alkynes;    benzotriazole;    amine-free;    copper-free.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

An efficient Pd-catalysed Sonogashira coupling reaction was achieved in the absence of copper and amine with inorganic base using phosphene-free, air stable di(1𝐻-benzo[𝑑][1,2,3]triazol-1-yl)methane as ligand. The cross coupling of electron-rich, electron-defficient and hindered aryl halides with terminal alkynes afforded the internal alkynes in good to excellent yields.

【 授权许可】

Unknown