Rapid and highly efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) catalysed by in situ generated I2 using Oxone®/KI or cerium ammonium nitrate (CAN)/KI systems under mild conditions

Journal of Chemical Sciences

Eskandar Kolvari1¹  Maryam Gilandoust²  Neda Bakhit²  Nadiya Koukabi²  Ardeshir Khazaei2²  Mohammad Ali Zolfigol2² 

[1] Department of Chemistry, Faculty of Science, Semnan University, Semnan, Iran$$;Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Post Box No. 4135, Iran$$

关键词: Alcohols;    phenols;    hexamethyldisilazane;    Oxone®/KI;    CAN/KI;    in situ generated I2;    trimethylsilylation.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Structurally diverse alcohols and phenols were trimethylsilylated in clean and efficient reactions with hexamethyldisilazane (HMDS) in the presence of a catalytic amount of I2 generated in situ from Oxone®/KI or CAN/KI systems. The reactions occur rapidly in good to high yields in wet CH2Cl2 at room temperature.

【 授权许可】

Unknown