Guest-host interactions in the cleavage of phenylphenyl acetates by 𝛽-cyclodextrin in alkaline medium

Journal of Chemical Sciences

T Chandrakala¹  K Rajasekaran1¹  V Raj¹ 

[1] Post Graduate Department of Chemistry, VHNSN College, Virudhunagar 626 002$$

关键词: Phenylphenyl acetate;    𝛽-cyclodextrin;    hydrophobic interactions;    guest-host complexes.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Kinetics of cleavage of phenylphenyl acetates (PPA) and several para-substituted PPAs in basic aqueous sodium carbonate-bicarbonate buffer containing 𝛽-cyclodextrin (CD) have been studied. The reaction exhibits saturation type kinetics and CD accelerates the rate of cleavage by the formation of 1G : 1H inclusion complex. The kinetic results indicate that aryloxy moiety of PPA is included in the hydrophobic cavity of CD. The overall rate constants for the cleavage of the [CD-ester] complex correlate with the Hammett 𝜎-constants and Hansch hydrophobicity parameters 𝜋. At higher concentrations of CD, there is an additional catalysis due to the formation of weak 1G : 2H complex.

【 授权许可】

Unknown