Synthetic studies on taxanes: A domino-enyne metathesis/Diels-Alder approach to the AB-ring

Journal of Chemical Sciences

Sandip A Pujari¹  Velayutham Ravikumar¹  Krishna P Kaliappan1¹ 

[1] Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400 076$$

关键词: Taxol;    RCM;    Grubbs catalyst;    IMDA;    Anticancer;    Domino reaction.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

A domino enyne cross-metathesis/intramolecular Diels-Alder reaction has been successfully used to synthesize a bicyclo[5.3.1] undecene, corresponding to AB-ring of taxol without the gem dimethyl group.

【 授权许可】

Unknown