Facilitation of peptide fibre formation by arginine-phosphate/carboxylate interactions

Journal of Chemical Sciences

K Krishna Prasad¹  Sandeep Verma1¹ 

[1] Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208 016$$

关键词: Peptide;    self-assembly;    arginine;    microscopy.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

This study describes peptide fibre formation in a hexapeptide, derived from the V3 loop of HIV-1, mediated by the interactions between arginine residues and phosphate/carboxylate anions. This charge neutralization approach was further confirmed when the deletion of arginine residue from the hexapeptide sequence resulted in fibre formation, which was studied by a combination of microscopic techniques.

【 授权许可】

Unknown