A new bile acid-derived lariat-ether: Design, synthesis and cation binding properties

Journal of Chemical Sciences

P Babu¹  Uday Maitra1¹ 

[1] Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India$$

关键词: Crown ether;    chola crown;    bile acid;    metal ion binding.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

A new chola lariat ether (1, a 21-crown-6) was constructed from readily available precursors. The association constant of compound 1 with alkali metal picrates was measured using Cram’s extraction protocol. Evidence is presented for the involvement of the 3-methoxy group for the complexation. Energy minimised structures show that the A-ring gets slightly distorted upon metal ion binding.

【 授权许可】

Unknown