Complete genome sequence of Hymenobacter sp. DG25A, a gamma radiation-resistant bacterium isolated from soil

Molecular & Cellular Toxicology

Hee-Young Jung²  Myung Kyum Kim¹  Sathiyaraj Srinivasan¹  Seung-Yeol Lee³ 

[1] Seoul Women’s University$$;Kyungpook National University$$Kyungpook National University$$;Kyungpook National University$$

关键词: Genome sequence;   

DOI  :  10.1007/s13273-017-0007-8

学科分类：分子生物学，细胞生物学和基因

来源: Korean Society of Toxicogenomics and Toxicoproteomics

【 摘 要 】

A gram-negative, rod-shaped, non-motile, gamma and UV-tolerant bacterium, Hymenobacter sp. DG25A, was isolated from a soil sample collected in South Korea. The isolated strain demonstrated high level of resistance against gamma irradiation, with a D10 value of 6 kGy. The complete genome of Hymenobacter sp. DG25A was found to consist of a single chromosome (3,777,136 bp). The bacterium was isolated from a gamma ray-irradiated soil sample and was found to contain enzymes involved in the accumulation of manganese, which protects proteins from oxidation by reactive oxygen species. The genome also encodes enzymes for the nucleotide excision repair pathway, which leads to the efficient removal of double-strand breaks caused by ionizing radiation such as gamma and UV rays. An understanding of these genomic features can potentially be used in several biotechnological applications such as for the degradation of harmful contaminants or radioactive waste.

【 授权许可】

Unknown