Panitumumab: An Arrow on Target

Pathology & Oncology Research

László Kopper¹ 

[1] Semmelweis University$$

关键词: Anti-EGFR therapy;   

DOI  :  10.1007/s12253-010-9257-7

学科分类：生理学与病理学

来源: Springer

【 摘 要 】

Several options are available today in the treatment of advanced colorectal cancer: traditional chemotherapeutic regimens, targeted therapies, and their combinations. Panitumumab is a new, fully human anti-EGFR monoclonal antibody, what is well-tolerated, effective as a single agent in chemotherapy refractory patients and in different combinations. The clinical response is restricted to tumors with wild-type RAS, therefore the RAS status should be checked before treatment.

【 授权许可】

Unknown