Diagnostic Concordance in Reporting Breast Needle Core Biopsies using the B Classification—A Panel in Italy

Pathology & Oncology Research

Saverio Caini¹  Maria Grazia Cattani²  Mauro Biancalani³  Vania Vezzosi⁴  Domenico Palli¹  Simonetta Bianchi⁴ 

[1] Cancer Research and Prevention Institute-ISPO$$;Bellaria Hospital$$;Empoli Hospital$$;University of Florence$$

关键词: Diagnostic concordance;   

DOI  :  10.1007/s12253-009-9176-7

学科分类：生理学与病理学

来源: Springer

【 摘 要 】

The widespread implementation of mammography screening has resulted in an increased frequency of needle core biopsies (NCB). The aim of this study was that of evaluating the diagnostic reproducibility on breast NCB, according to the B-classification, among several pathologists from different Italian regions. Fifty single slides of NCBs performed for non palpable breast lesions were selected to evaluate the diagnostic reproducibility, according to the B classification, among 31 pathologists from different Italian areas, involved in the pathologic diagnosis of screen-detected breast lesions. According to the study majority diagnosis (MD), 21 cases were classified as B2 (benign lesion), 23 B3 (lesion of uncertain malignant potential) and 6 B5 (malignant lesion). Overall, individual kappa coefficients in comparison to MD were good (mean 0.61, range 0.31�?0.88). The level of inter-observer agreement, however, appeared lower in differentiating the two intermediate categories B2 and B3, thus potentially leading to over-treatment (false-positives: 26%) or under-treatment (false-negatives: 17%) of individual patients. Specific sub-types of B3 need an improvement of the diagnostic definition. A multidisciplinary approach and consultation with expert colleagues are recommended.

【 授权许可】

Unknown