E-Cadherin expression in transitional cell carcinomas

Pathology & Oncology Research

Eszter Székely¹  Imre Romics¹  Péter Riesz¹  Virág Török¹  Tamás Székely¹ 

[1] Semmelweis University$$

关键词: transitional cell carcinoma;   

DOI  :  10.1007/BF02893447

学科分类：生理学与病理学

来源: Springer

【 摘 要 】

The authors analyzed the expression of E-cadherin, one of the most important cell adhesion molecules, on paraffin sections of tumors of bladder cancer patients. The aim of the study was to see whether there is any association between E-cadherin expression and tumor grade, stage, age and gender of the patients, number of recurrences, or overall survival. The samples were examined in 51 primary bladder transitional cell carcinomas (TCC) of 50 patients, resected by transurethral resection (TUR) between January 1, 1996 and January 1, 1997. Immunoreactions were performed with monoclonal anti-human E-cadherin antibody. Forty of the fifty patients could be clinically followed. The analysis of the results on these forty patients was performed by contingency analysis and significance was assessed by Ξ² test. No significant association between E-cadherin expression and tumor grade, stage, age or gender of the patients, the number of recurrences, or overall survival could be seen. (Pathology Oncology Research Vol 12, No 2, 73�?77)

【 授权许可】

Unknown