Embryotoxicity and teratogenicity of some derivatives of chloroethylaminophenylacetic acid

Pathology & Oncology Research

Janina ŽUkienɹ  Gražina GraŽElienɹ  Janina DidŽiapetrienɹ  Giedre SinkeviČiÚtɹ  Violeta Žalgevicienɹ 

[1] Faculty of Medicine of Vilnius University and Department of the Experimental Therapy of Lithuanian Oncology Center$$

关键词: antitumor agents;   

DOI  :  10.1007/BF02904691

学科分类：生理学与病理学

来源: Springer

【 摘 要 】

Embryotoxic and teratogenic properties of Lophenal, Phenalon, Pharanox and Pharanoxi selenate were investigated experimentally. All examined antitumour agents showed embryotoxic effects. Lophenal, Phenalon and Pharanox had teratogenic effects. By modifying the structure of Pharanox with selenium a reduction in teratogenic effect was achieved.

【 授权许可】

Unknown