Total IgA and IgG in sera of patients with different primary malignancies

Pathology & Oncology Research

Maja Popovic³  Zoran Pisl¹  Ante Roguljic²  Palma Efenberger-Marinculic¹  Terezija M Hrzenjak³ 

[1]Institute for Medical Research and Occupational Health$$

[2]Clinic for Tumors and Allied Diseases$$

[3]University of Zagreb$$

关键词: malignant tumors;   

DOI  :  10.1007/BF02893953

学科分类：生理学与病理学

来源: Springer

【 摘 要 】

The concentrations of total serum IgA and IgG of 267 patients with different primary malignant tumors were measured by ELISA. Total serum IgA increased by 30% to 40% in patients with malignancies associated with mucous membranes (nasopharyngeal, gastrointestinal and bronchial carcinomas), while the change in total serum IgG was negligible. Although, the changes in Ig level could be influenced by many host factors, these data call attention to the potential indicative role of total serum IgA levels. Further studies are required to establish links between serum IgA levels and stages of tumor growth or tumor progression in order to use these values as prognostic factors.

【 授权许可】

Unknown