Lactam nonanic acid, a new substance from Cleome viscosa with allelopathic and antimicrobial properties

Journal of biosciences

Anirban Jana¹  Suparna Mandal Biswas1¹ 

[1] Agricultural and Ecological Research Unit, Indian Statistical Institute, 203, BT Road, Calcutta 700 108, India$$

关键词: Allelochemical;    antimicrobial activity;    Cleome viscosa L.;    lactam nonanoic acid (LNA);    root exudates;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Cleome viscosa L. (Capparidaceae) is well known for its medicinal properties. Lactam nonanoic acid (LNA) [2-amino-9-(4-oxoazetidin-2-yl)-nonanoic acid; C12H22N2O3, mol. wt. 242] has been isolated and purified from the root exudates of Cleome viscosa. The aqueous solution of this pure compound has been tested on bacteria (Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus) and fungi (Aspergillus fumigatus, A. niger and A. tamarii). At a dosage of 500 ppm and above, P. aeruginosa and S. aureus were totally inhibited while E. coli remained unaffected. On the other hand, growth of A. niger and A. tamarii was stimulated while there was no effect on A. fumigatus. This pure compound showed concentration-dependent inhibitory activity on rice, gram and mustard seeds.

【 授权许可】

Unknown