Investigation into the molecular function of the neuronal Hu RNA binding protein, HuCsv1

Journal and Proceedings of the Royal Society of New South Wales

McCarthy, Peter¹ 

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关键词: settlement strategies;    climate fluctuations;    Neolithic;    Eneolithic;    Central Europe;    Slovakia;   

DOI  :  

来源: Royal Society of New South Wales

【 摘 要 】

Of the four Hu genes found in most vertebrates (HuA, HuB, HuC and HuD), all except HuA exhibit mRNA and protein expression that is essentially restricted to post-mitotic neurons of the developing and adult nervous systems. Spatial and temporal examination of individual "neuronal Hu" (nHu = HuB, HuC and HuD) proteins in brain tissue suggests nHu proteins may play a functional role during neuronal differentiation; as RNA-binding proteins, the nHu proteins may participate in gene regulatory events that are essential for acquisition of the neuronal phenotype.

【 授权许可】

Unknown