LINE-1 distribution in six rodent genomes follow a species-specific pattern

Journal of genetics

A. Vieira-Da-Silva¹  F. Adega¹  R. Chaves1¹  H. Guedes-Pinto¹ 

[1] Department of Genetics and Biotechnology (DGB), Laboratory of Cytogenomics and Animal Genomics (CAG), University of Trás-os-Montes and Alto Douro (UTAD), 5001, 801 Vila Real, Portugal$$

关键词: LINE-1;    rodentia;    physical mapping;    heterochromatin;    karyotype evolution.;   

DOI  :  

学科分类：生物科学（综合）

来源: Indian Academy of Sciences

【 摘 要 】

L1 distribution in mammal’s genomes is yet a huge riddle. However, these repetitive sequences were already found in all chromosomic regions, and in general, they seem to be nonrandomly distributed in the genome. It also seems that after insertionand when they are not deleterious, they are always involved in dynamic processes occurring on that particular chromosomic region. Furthermore, it seems that large-scale genome rearrangements and L1 activity and accumulation are somehow interconnected. In the present study, we analysed L1 genomic distribution in Tatera gambiana (Muridae, Gerbillinae), Acomys sp. (Muridae, Deomyinae), Cricetomys sp. (Nesomyidae, Cricetomyinae), Microtus arvalis (Cricetidae, Arvicolinae), Phodopus roborovskii and P. sungorus (Cricetidae, Cricetinae). All the species studied here seems to exhibit a species-specific pattern.Possible mechanisms, and processes involved in L1 distribution and preferential accumulation in certain regions are discussed.

【 授权许可】

Unknown