Estimating genetic correlations based on phenotypic data: a simulation-based method

Journal of genetics

Elias Zintzaras1 2¹ 

[1] Department of Biomathematics, University of Thessaly School of Medicine, 2 Panepistimiou Str., Biopolis, Larissa 41110, Greece$$

关键词: correlation;    genetics;    phenotype;    environment;    bias;    simulation.;   

DOI  :  

学科分类：生物科学（综合）

来源: Indian Academy of Sciences

【 摘 要 】

Knowledge of genetic correlations is essential to understand the joint evolution of traits through correlated responses to selection, a difficult and seldom, very precise task even with easy-to-breed species. Here, a simulation-based method to estimate genetic correlations and genetic covariances that relies only on phenotypic measurements is proposed. The method does not require any degree of relatedness in the sampled individuals. Extensive numerical results suggest that the propose method may provide relatively efficient estimates regardless of sample sizes and contributions from common environmental effects.

【 授权许可】

Unknown