Genotype–environment interaction for total fitness in Drosophila

Journal of genetics

James D. Fry1¹ 

[1] Department of Biology, University of Rochester, Rochester NY 14627-0211, USA$$

关键词: antagonistic pleiotropy;    balancer chromosomes;    environmental heterogeneity;    maintenance of genetic variation;    trade-offs.;   

DOI  :  

学科分类：生物科学（综合）

来源: Indian Academy of Sciences

【 摘 要 】

A fundamental assumption of models for the maintenance of genetic variation by environmental heterogeneity is that selection favours different genotypes in different environments. Here, I use a method for measuring total fitness of chromosomal heterozygotes in Drosophila melanogaster to assess genotype–environment interaction for fitness across two ecologically relevant environments, medium with and without added ethanol. Two-third chromosomes are compared, one from a population selected for ethanol tolerance, and the other from a control population. The results show strong crossing of reaction norms for outbred, total fitness, with the chromosome from the ethanol-adapted population increasing fitness on ethanol-supplemented food, but decreasing fitness on regular food, relative to the chromosome from the control population. Although I did not map the fitness effects below the chromosome level, the method could be adapted for quantitative trait locus mapping, to determine whether a substantial proportion of fitness variation is contributed by loci at which different alleles are favoured in different environments.

【 授权许可】

Unknown