期刊论文详细信息
Journal of genetics
An orphan gyrB in the Mycobacterium smegmatis genome uncovered by comparative genomics
P. Jain1  V. Nagaraja11 
[1] Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560 012, India$$
关键词: Mycobacterium smegmatis;    gyr genes;    DNA gyrase;    topoisomerase;    comparative genomics.;   
DOI  :  
学科分类:生物科学(综合)
来源: Indian Academy of Sciences
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【 摘 要 】

DNA gyrase is an essential topoisomerase found in all bacteria. It is encoded by gyrB and gyrA genes. These genes are organized differently in different bacteria. Direct comparison of Mycobacterium tuberculosis and Mycobacterium smegmatis genomes reveals presence of an additional gyrB in M. smegmatis flanked by novel genes. Analysis of the amino acid sequence of GyrB from different organisms suggests that the orphan GyrB in M. smegmatis may have an important cellular role.

【 授权许可】

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