期刊论文详细信息
Eurasian Journal of Analytical Chemistry | |
Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Beclomethasone Dipropionate and Clotrimazole | |
Abhishek D. Ogale1  Santosh Vilaschand Gandhi1  | |
关键词: high performance liquid chromatography (HPLC); beclomethasone dipropionate; clotrimazole; stability indicating; validation; | |
DOI : 10.12973/ejac.2017.00177a | |
学科分类:分析化学 | |
来源: Eurasian Journal of Analytical Chemistry | |
【 摘 要 】
The aim of the present study was to develop a validated stability indicating reverse phase high performance liquid chromatography (RP-HPLC) method for simultaneous estimation of Beclomethasone dipropionate (BEC) and Clotrimazole (CL) in bulk and combined dosage form ( CLOCIP-B cream). An isocratic, RP-HPLC method was developed using Hi Q Sil C18 (250 x 4.6 mm, 5 μm) column using 1 mM ammonium acetate buffer and acetonitritle (10:90 v/v) as mobile phase at flow rate of 1 ml/min at detection wavelength of 223 nm.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912020435446ZK.pdf | 840KB | download |